Effectiveness of Snake Antivenom: Species and Regional Venom Variation and Its Clinical Impact
نویسندگان
چکیده
The ubiquity of venom variation in snakes poses special problems for the manufacture of antivenom and has undermined the commercial attractiveness of this class of therapeutic agent. In particular, it has been amply documented that both interspecific and intraspecific variation in venom composition can affect the neutralisation capacity of antivenoms. This may be exacerbated by the selective use of tests of venom toxicity *Correspondence: Bryan G. Fry, Australian Venom Research Unit, Department of Pharmacology, University of Melbourne, Victoria 3010, Australia; E-mail:
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